Dr. Chen Chen is an Assistant Professor of Information Systems at The Chinese University of Hong Kong, Shenzhen. He obtained his Ph.D. in Molecular Cancer Biology from  Duke University in 2014, and is expected to obtain his Ph.D. in Management from Boston University. His primary research interest is to use advanced machine learning algorithms to decipher how human beings interact, behave and make decisions in both virtual and real communities.

Academic Publications

Under Review


1. Chen Chen & Dylan Walker. A Bitter Pill to Swallow? The Consequences of Patient Evaluation in Online Health Q&A Platforms. (Under R&R at Information Systems Research, UTD24) (Part of the three-paper dissertation)

2. Chen Chen, Dylan Walker, Venkatesh Saligrama & Henghui Zhu. Political Slant: How You Talk about What You Talk About! (Under Review at Conference on Neural Information Processing Systems (NeurIPS))


Working Paper


1. Chen Chen, Dylan Walker, Venkatesh Saligrama & Henghui Zhu. Navigating the Congress: Explore the True Ideology of The US Politicians and its Impact on their Votes. (Stage: manuscript writing; Target: Proceedings of the National Academy of Sciences) (Part of the three-paper dissertation)

2. Chen Chen, Dylan Walker, Venkatesh Saligrama & Henghui Zhu. When do the Bill Pass: Using Deep Neural Network to Predict and Explain When a Bill Gets Passed. (Stage: data analysis; Target: Science)

3. Chen Chen, Dylan Walker & Jayakanth Srinivasan. Learning from the Wild-Wild West of Online Health. (Stage: ready for submission; Target: Health Affairs, a top journal in public health)

4. Lan Wang, Chen Chen & Xiao-ping Chen. Compassion and Learning in Online Communities. (Stage: data analysis; Target: Organization Science)


Peer Reviewed Articles in Scientific Journals


1. Chen C, Zhang L, Huang NJ, Huang B, Kornbluth S. (2013). Suppression of DNA-damage checkpoint signaling by Rsk-mediated phosphorylation of Mre11. Proceedings of the National Academy of Sciences. 110(51):20605-20610. Impact factor: 9.8

2. Wu JQ, Guo JY, Tang W, Yang CS, Freel CD, Chen C, Nairn AC, Kornbluth S. (2009). PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation. Nature Cell Biology. 11(5):644-651. Impact factor: 20.1

3. Tang W, Wu JQ, Chen C, Yang CS, Guo JY, Freel CD, Kornbluth S. (2010). Emi2-mediated inhibition of E2-substrate ubiquitin transfer by the anaphase-promoting complex/cyclosome through a D-box-independent mechanism. Molecular Biology of the Cell. 21(15):2589-2597. Impact factor: 4.5

4. Zhang L, Huang NJ, Chen C, Tang W, Kornbluth S. (2012). Ubiquitylation of p53 by the APC/C inhibitor Trim39. Proceedings of the National Academy of Sciences. 109(51):20931-209306. Impact factor: 9.8

5. Huang NJ, Zhang L, Tang W, Chen C, Yang CS, Kornbluth S. (2012). The Trim39 ubiquitin ligase inhibits APC/Cdh1-mediated degradation of the Bax activator MOAP-1. Journal of Cell Biology. 197(3):361-367. Impact factor: 9.7

6. Huang BF, Yang CS, Wojton J, Huang NJ, Chen C, Soderblom EJ, Zhang L, Kornbluth S. (2014). Metabolic control of Ca2+/Calmodulin-dependent protein kinase II (CaMKII)-mediated Caspase-2 suppression by the B55β/protein phosphatase 2A (PP2A). Journal of Biological Chemistry. 289(52), 35882-35890; Impact factor: 4.6