Publications
Publications
Research Assistant Professor
Molecular Pharmacology, Cancer Biology, Molecular Cellular Mechanisms
1. Choi HJ, Song JH, Stephanie C, Bishop, Chun-Feng Liu and Zhu BT [2020] Norephinephrine and Dopamine, Two Catecholamine Neurotransmitters, Have protective Effect against Glutathione Depletion-Associated Oxidative Neuronal Death. (pending revision)
2. Choi HJ, Anthony J. Lee, Ki Sung Kang, Ji Hoon Song and Bao Ting Zhu [2020] Hydroxyestrone, an Endogenous Estrogen Metabolite, Can Strongly Protect Neuronal Cells Against Oxidative Damage. Sci Rep. 2020 Apr 29;10(1):7283. doi: 10.1038/s41598-020-62984-y.
3.Choi HJ, Zhu BT [2019]. Upregulated cyclin B1/CDK1 mediates apoptosis following 2-methoxyestradiol-induced mitotic catastrophe: Role of Bcl-XL phosphorylation. Steroids. 2019 Feb 22. pii: S0039-128X(19)30045-5. doi: 10.1016/j.steroids.
4. Choi HJ, Heo JH, Park JY, Jeong JY, Cho HJ, Park KS, Kim SH, Moon YW, Kim JS, An HJ [2019]. A novel PI3K/mTOR dual inhibitor, CMG002, overcomes the chemoresistance in ovarian cancer. Gynecol Oncol. 2019 Apr;153(1):135-148. doi: 10.1016/j.ygyno.
5. Ogony J, Choi HJ, Lui A, Cristofanilli M, Lewis-Wambi [2016]. Interferon-induced transmembrane protein 1 (IFITM1) overexpression enhances the aggressive phenotype of SUM149 inflammatory breast cancer cells in a signal transducer and activator of transcription 2 (STAT2)-dependent manner. Breast Cancer Res. 2016 Feb 20;18(1):25.
6. Fukui M, Yamabe N, Choi HJ, Polireddy K, Chen Q and Zhu BT [2015] Mechanism of Ascorbate-Induced Cell Death in Human Pancreatic Cancer Cells: Role of Bcl-2, Beclin 1 and Autophagy. Planta Med 2015; 81(10): 838-846. DOI: 10.1055/s-0035-1546132
7. Yee SB, Choi HJ, Chung SW, Park DH, Sung B, Chung HY and Kim ND [2015] Growth inhibition of luteolin on HepG2 cells is induced via p53 and Fas/Fas-ligand besides the TGF-β pathway. Int J Oncol. 2015 Jun 18. doi: 10.3892/ijo.2015.3053
8. Choi HJ, Asona Lui, Joshua Ogony, Rifat Jan, Peter Sims, and Joan Lewis-Wambi [2015] Targeting interferon signaling pathway sensitizes aromatase inhibitor resistant breast cancer cells to estrogen-induced cell death. Breast Cancer Research 17(1):6. doi: 10.1186/s13058-014-0506-7
9. Choi HJ, Zhu BT [2012]. Role of cyclin B1/Cdc2 in mediating Bcl-X(L) phosphorylation and apoptotic cell death following nocodazole-induced mitotic arrest. Mol Carcinog. doi: 10.1002/mc.21956.
10.Choi HJ, Zhu BT [2012]. Critical role of cyclin B1/Cdc2 up-regulation in the induction of mitotic prometaphase arrest in human breast cancer cells treated with 2-methoxyestradiol. Biochim Biophys Acta. 1823:1306-1315. (I.F. = 5.538)
11. Fukui M, Choi HJ, Zhu BT [2012]. Rapid generation of mitochondrial superoxide induces mitochondrion-dependent but caspase-independent cell death in hippocampal neuronal cells that morphologically resembles necroptosis. Toxicol Appl Pharmacol. 262:156-166. (I.F. = 4.447)
12. Fu X, Wang P, Fukui M, Long C, Yin L, Choi HJ, Zhu BT [2012]. PDIp is a major intracellular oestrogen-storage protein that modulates tissue levels of oestrogen in the pancreas. Biochem J. 447:115-23. (I.F. = 5.016)
13. Choi HJ, Fukui M and Zhu BT [2011] Role of cyclin B1/Cdc2 up-regulation in the development of mitotic prometaphase arrest in human breast cancer cells treated with nocodazole. PLoS ONE 6: e24312. (I.F. = 4.411)
14. Choi HJ, Kang KS, Fukui M and Zhu BT [2011] Critical role of the JNK-p53-GADD45α apoptotic cascade in mediating oxidative cytotoxicity in hippocampal neurons. Br. J. Pharmacol. 162: 175-192. (I.F. = 5.259)
15. Fukui M, Choi HJ and Zhu BT [2010]. Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death. Free Radic. Biol. Med. 49: 800-813. (I.F. = 5.773)
16. Fukui M, Song JH, Choi J, Choi HJ and Zhu BT [2009] Mechanism of glutamate-induced neurotoxicity in HT22 mouse hippocampal cells. Eur. J. Pharmacol. 617: 1-11. (I.F. = 2.737)
17. Zhou R, Fukui M, Choi HJ and Zhu BT [2009] Induction of a reversible, non-cytotoxic S-phase delay by resveratrol: Implications for a mechanism of lifespan prolongation and cancer protection. Br. J. Pharmacol. 158: 462-474. (I.F. = 5.259)
18. Fukui M, Choi HJ, Weinman SA, Okada K and Zhu BT [2012] Mechanism of herbicide-induced neuronal death: Evidence for mitochondrial oxidative damage as the main cause. Molecular and Cellular Biochemistry (in press). (I.F. = 3.122)
19. Choi HJ, Chung YS, Kim HJ, Moon UY, Choi YH, Van Seuningen I, Baek SJ, Yoon HG and Yoon JH [2009] Signal pathway of 17β-estradiol-induced MUC5B expression in human airway epithelial cells. Am. J. Resp. Cell Mol. Biol. 40: 168-178. (I.F. = 4.109)
20. Choi HJ, Yee SB, Park SE, Im E, Jung JH, Chung HY, Choi YH and Kim ND [2006] Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases. Cancer Lett. 232: 214-225. (I.F. = 5.992)
21. Choi HJ, Choi YH, Yee SB, Im E, Jung JH and Kim ND [2005] Ircinin-1 induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells. Mol. Carcinog. 44: 162-173. (IF = 4.77)
22. Choi HJ, Bae SJ, Kim ND, Jung JH and Choi YH [2005] Induction of apoptosis by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp. in human skin melanoma cells. Int. J. Mol. Med. 14: 1091-1096. (I.F. = 1.88)
23. Park SE, Choi HJ, Yee SB, Chung HY, Suh H, Choi YH, Yoo YH and Kim ND [2004] Synthetic bile acid derivatives inhibit cell proliferation and induce apoptosis in HT-29 human colon cancer cells. Int. J. Oncol. 25: 231-236. (I.F. = 2.447)
24. Choi HJ, Kim ND, Jung JH and Choi YH [2004] Regulation of Bcl-2 family and cyclooxygenases by furanoterpenoids isolated from marine sponges in human lung cancer A549 cells. Korean J. Life Sci. 14: 445-452.
25. Choi HJ, Jung MJ and Jeong YK [2002] Optimization of the production of an immunostimulant from a marine macterium. Korean J. Life Sci. 12: 759-764.
26. Choi YH and Choi HJ [2001] Significance of cell cycle and checkpoint control. Korean J. Life Sci. 11: 362-370. (review article)
27. Choi HJ, Jung MJ and Jeong YK [2000] Isolation and identification of a marine bacterium producing an immunostimulant. J. Korean Soc. Food Sci. Nutr. 29: 1145-1150.