Biography

Prof. Tianwei Yu graduated at the Biology Department of Tsinghua University in 1997, obtained his master’s degree of Biochemistry & Molecular Biology in 2000 at Tsinghua University and another master’s degree of Biochemistry & Molecular Biology in 2004 at UCLA, then earned his Ph.D. of statistics at UCLA in 2005. 

From 2006 till Feb 2020, Yu taught in the Department of Biostatistics and Bioinformatics at Emory University. He was a tenured professor before leaving the post to join CUHK-SZ. Yu’s research is focused on bioinformatics and applied machine learning. He is interesed in applications in metabolomics, pharmacogenomics, and systems biology. In his collaborative research, he works on enrironmental health, virology/vaccinology, nutrition, and cancer. 

Research

My methodological research is focused on developing new algorithms and software for the analysis of high dimensional omics data. The research can be roughly divided into three categories: modeling large-scale biological networks, detecting nonlinear and complex associations in high-dimensional data, and metabolomics data preprocessing. In addition, I collaborate extensively with biomedical researchers, both using bioinformatics tools and traditional statistical methods.


Awards and Honors
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Academic Publications

Kong Y, Yu T (2020) forgeNet: a graph deep neural network model using tree-based ensemble classifiers for feature graph construction. Bioinformatics. (Accepted)

Fei T, Yu T (2020) scBatch: Batch Effect Correction of RNA-seq Data through Sample Distance Matrix Adjustment. Bioinformatics. (Epub ahead of print)

Cai Q, Kang J#Yu T# (2020) Bayesian network marker selection via the thresholded graph Laplacian Gaussian prior. Bayesian Analysis 15(1): 79-102 (#Correspondence authors)

Rasheed MAU, Hickman CJ, McGrew M, Sowers SB, Mercader S, Hopkins A, Grimes V, Yu T, Wrammert J, Mulligan MJ, Bellini WJ, Rota PA, Orenstein WA, Ahmed R, Edupuganti S. (2019) Decreased humoral immunity to mumps in young adults immunized with MMR vaccine in childhood.  Proc Natl Acad Sci USA. 116(38):19071-19076.

Bellissimo MP, Cai Q, Ziegler TR, Liu KH, Tran PH, Vos MB, Martin GS, Jones DP, Yu T, Alvarez JA (2019) Plasma High-Resolution Metabolomics Differentiates Adults with Normal Weight Obesity from Lean Individuals. Obesity 27(11):1729-1737.

Chamcha V, Reddy PBJ, Kannanganat S, Wilkins C, Gangadhara S, Velu V, Green R, Law GL, Chang J, Bowen JR, Kozlowski PA, Lifton M, Santra S, Legere T, Chea LS, Chennareddi L, Yu T, Suthar MS, Silvestri G, Derdeyn CA, Gale M Jr, Villinger F, Hunter E, Amara RR (2019) Strong Vaccine-Elicited Th1-Biased CD4 T cell Response Is Associated With Diminished SIV Vaccine Efficacy. Science Translational Medicine, 11(519). 

Kong Y, Yu T (2019) A hypergraph-based method for large-scale dynamic correlation study at the transcriptomic scale. BMC Genomics. 20:397.

Davis CW, Jackson KJL, McElroy AK, Halfmann P, Huang J, Chennareddy C, Piper AE, Leung Y, Albari?o CG, Crozier I, Ellebedy AH, Sidney J, Sette A, Yu T, Nielsen SCA, Goff AJ, Spiropoulou CF, Saphire EO, Cavet G, Kawaoka Y, Mehta AK, Glass PJ, Boyd SD, Ahmed R. (2019) Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection. Cell177(6):1566-1582.

 Liang D, Ladva CN, Golan R, Yu T, Walker D, Sarnat SE, Greenwald R, Uppal K, Tran V, Jones DP, Russell AG, Sarnat GA (2019) Perturbations of the Arginine Metabolome Following Exposures to Traffic-Related Air Pollution in a Panel of Commuters with and without Asthma. Environmental International127:503-513.

 Lu J*, Lu Y*, Ding Y*, Xiao Q, Liu L, Cai Q, Kong Y, Bai Y#Yu T# (2019) DNLC: Differential Network Local Consistency Analysis. BMC Bioinformatics. 20(Suppl 15):489. (*Equal contribution, #Correspondence authors)

Kong Y, Yu T (2018) A deep neural network model using Random Forest to extract feature representation for gene expression data classification. Scientific Reports. 8(1):16477. 

Connolly S, Wall KM, Tang J, Yu T, Kilembe W, Kijak G, Allen S, Hunter E. (2018) Fc-gamma receptor IIA and IIIA variants in two African cohorts: Lack of consistent impact on heterosexual HIV acquisition, viral control, and disease progression. Virology. 525:132-142. 

Ladva CN, Golan R, Liang D, Greenwald R, Walker DI, Uppal K, Raysoni AU, Tran V, Yu T, Flanders WD, Miller GW, Jones DP, Sarnat JA. (2018) Particulate metal exposures induce plasma metabolome changes in a commuter panel study. PLoS One. 13(9): e0203468.

Yu T (2018) A new dynamic correlation algorithm reveals novel functional aspects in single cell and bulk RNA-seq Data. PLoS Computational Biology. 14(8):e1006391.

 Liang D, Moutinho JL, Golan R, Yu T, Ladva CN, Niedzwiecki M, Walker DI, Sarnat SE, Chang HH, Greenwald R, Jones DP, Russell AG, Sarnat JA (2018) Use of high-resolution metabolomics for the identification of metabolic T signals associated with traffic-related air pollution. Environment International. 120: 145–154. 

Kong Y, Yu T (2018) A graph-embedded deep feedforward network for disease outcome classification and feature selection using gene expression data. Bioinformatics. 34(21):3727-3737.

Yu T (2018) Nonlinear variable selection with continuous outcome: a fully nonparametric incremental forward stagewise approach. Statistical Analysis and Data Mining. 11(4):188-197.

Fei T, Zhang T, Shi W#Yu T# (2018) Mitigating the adverse impact of batch effects in sample pattern detection. Bioinformatics. 34, 2634-2641. (#Correspondence authors)

Jin Z, Kang J#Yu T# (2018) Missing value imputation for LC-MS metabolomics data by incorporating metabolic network and adduct ion relations. Bioinformatics. 34(9):1555-1561. (#Correspondence authors)

Ladva CN, Golan R, Greenwald R, Yu T, Sarnat SE, Flanders WD, Uppal K, Walker DI, Tran V, Liang D, Jones DP, Sarnat J. (2017) Metabolomic profiles of plasma, exhaled breath condensate, and saliva are correlated with potential for air toxics detection. J Breath Res. 12(1):016008.

 Wang Y, Wu H#Yu T# (2017) Differential Gene Network Analysis from Single Cell RNA-Seq. J. Genet. Genomics. 44(6):331-334. (#Correspondence authors)

Rouphael NG, Paine M, Mosley R, Henry S, McAllister DV, Kalluri H, Pewin W, Frew PM, Yu T, Thornburg NJ, Kabbani S, Lai L, Vassilieva EV, Skountzou I, Compans RW, Mulligan MJ, Prausnitz MR. (2017) The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial. Lancet. 390(10095):649-658. 

Li S, Sullivan NL, Rouphael N, Yu T, Banton S, Maddur MS, McCausland M, Chiu C, Canniff J, Dubey S, Liu K, Tran V, Hagan T, Duraisingham S, Wieland A, Mehta AK, Whitaker JA, Subramaniam S, Jones DP, Sette A, Vora K, Weinberg A, Mulligan MJ, Nakaya HI, Levin M, Ahmed R, Pulendran B. (2017) Metabolic Phenotypes of Response to Vaccination in Humans. Cell. 169(5):862-877.

Liao P, Wu H#Yu T# (2017) ROC Curve Analysis in the Presence of Imperfect Reference Standards. Statistics in Biosciences9(1):91-104. (#Correspondence authors)

Cai Q, Kang J#Yu T# (2017) Network Marker Selection for Untargeted LC/MS Metabolomics Data. J. Proteome Res. 16(3):1261-1269. (#Correspondence authors)

Chen Z, Yu T, Cabay RJ, Jin Y, Mahjabeen I, Luan X, Huang L, Dai Y, Zhou X (2017) miR-486-3p, miR-139-5p, and miR-21 as Biomarkers for the Detection of Oral Tongue Squamous Cell Carcinoma. Biomarkers in Cancer. 9:1-8.

Yan Y*, Qiu S*, Jin Z, Gong S, Bai Y#, Lu J#Yu T# (2017) Detecting subnetwork-level dynamic correlations. Bioinformatics. 33 (2): 256-265.  (*Equal contribution, #Correspondence authors)

Lan Z, Zhao Y, Kang J#Yu T# (2016) Bayesian Network Feature Finder (BANFF): an R package for gene network feature selection. Bioinformatics. 32(23):3685-3687. (#Correspondence authors)

Choi YH, Jin N, Kelly F, Sakthivel SK, Yu T (2016) Elevation of Alanine Aminotransferase Activity Occurs after Activation of the Cell-Death Signaling Initiated by Pattern-Recognition Receptors ?but before Activation of Cytolytic Effectors in NK or CD8+ T Cells in the Liver During Acute HCV Infection. PLoS One. 11(10):e0165533.

Mónaco D, Dilernia D, Gartland A, Yu T, Prince J, Dennis K, Qin K, Schaeffer M, Claiborne D, Killembe W, Tang J, Price M, Farmer P, Gillmour J, Bansal A, Allen S, Gopfert P, Hunter E (2016) Balance Between Transmitted HLA Pre-adapted and Non-associated Polymorphisms is a Major Determinant of HIV-1 Disease Progression. J Exp Med.213(10):2049-63.

Liu H, Li P, Zhu M, Wang X, Lu J#Yu T# (2016) Nonlinear network reconstruction from gene expression data using marginal dependencies measured by DCOL. PLoS ONE, 11(7):e0158247. (#Correspondence authors)

 He Q, Chen Z, Cab RJ, Zhang L, Luan X, Chen D, Yu T, Wang A, Zhou X. (2016) microRNA-21 and microRNA-375 from oral cytology as biomarkers for oral tongue cancer detection. Oral Oncology, 57: 15-20.

Chong E, Huang Y, Wu H, Ghasemzadeh N, Uppal K, Quyyumi AA, Jones DP, Yu T (2015) Local false discovery rate estimation using feature reliability in LC/MS metabolomics data. Sci Rep, 5: 17221.

Peng H, Ma J, Bai Y, Lu J#Yu T# (2015) MeDiA: Mean Distance Association and its Applications in Nonlinear Gene Set Analysis. PLoS ONE. 10(4):e0124620 (#Correspondence authors)

Claiborne DT, Prince JL, Scully E, Macharia G, Micci L, Lawson B, Kopycinski J, Deymier MJ, Vanderford TH, Nganou-Makamdop K, Ende Z, Brooks K, Tang J, Yu T, Lakhi S, Kilembe W, Silvestri G, Douek D, Goepfert PA, Price MA, Allen SA, Paiardini M, Altfeld M, Gilmour J, Hunter E. (2015) Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression. Proc Natl Acad Sci USA. 112(12):E1480-9. 

Wang K, Zhao Q, Lu J#Yu T# (2015) K-profiles: a nonlinear clustering method for pattern detection in high dimensional data. Biomed Res Int. 2015:918954 (#Correspondence authors)

Zhao J, Zhu Y, Hyun N, Zeng D, Uppal K, Tran VT, Yu T, Jones D, He J, Lee ET, Howard BV. (2015) Novel Metabolic Markers for the Risk of Diabetes Development in American Indians. Diabetes Care. 38(2):220-7.

Patel RM, Roback JD, Uppal K, Yu T, Jones DP, Josephson CD. (2015) Metabolomics profile comparisons of irradiated and nonirradiated stored donor red blood cells. Transfusion. 55(3):544-52. 

Yu T, Bai Y.  (2014) Network-based modular latent structure analysis. BMC Bioinformatics. 2014, 15(Suppl 13):S6. 

Yu T, Jones DP.  (2014) Improving peak detection in high-resolution LC/MS metabolomics data using preexisting knowledge and machine learning approach. Bioinformatics. 30(20):  2941-2948.

Kwa S, Lai L, Gangadhara S, Siddiqui M, Pillai VB, Labranche C, Johnson WE, Yu T, Earl PL, Moss B, Hirsch VM, Montefiori DC, Robinson HL, Kozlowski PA, Amara RR. (2014) CD40L-adjuvanted DNA/MVA SIV vaccine enhances SIV-specific humoral and cellular immunity, and improves protection against a heterologous mucosal SIV challenge. Journal of Virology, 88(17):9579-89.

Yang R, Bai Y, Qin ZS, Yu T. (2014) EgoNet: identification of human disease ego-network modules. BMC Genomics, 15(1):314.

Zhao Y*, Kang J*#Yu T#. (2014) A Bayesian non-parametric mixture model for selecting genes and gene subnetworks. Ann. Appl. Stat. 8(2): 999-1021. (#Correspondence authors)

Zhao J, Zhu Y, Uppal K, Tran VT, Yu T, Lin J, Matsuguchi T, Blackburn E, Jones D, Lee ET, Howard BV. (2014) Metabolic profiles of biological aging in American Indians: The strong heart family study. Aging, 6(3): 176-186.

Yu T, Peng H (2013) Hierarchical clustering of high-throughput expression data based on general dependencies. IEEE-ACM Trans. Comput. Biol. Bioinform10(4): 1080-85.

Yu T, Park Y, Li S, Jones DP (2013) Hybrid feature detection and information accumulation using high-resolution LC-MS metabolomics data. J. Proteome Res. 12(3):1419-27.

Yu T, Zhao Y, Shen S. (2013) AAPL: Assessing Association between P-value Lists. Stat. Anal. Data. Min.6(2):144-155.

Uppal K, Soltow QA, Strobel FH, Pittard WS, Gernert KM, Yu T, Jones DP. (2013) xMSanalyzer: automated pipeline for improved feature detection and downstream analysis of large-scale, non-targeted metabolomics data.BMC Bioinformatics, 14(1):15.

 Claiborne DT*, Prince JL*, Carlson J, Schaefer M, Yu T, Lahki S, Prentice H, Yue L, Vishwanathan A, Kilembe W, Goepfert P, Price M, Mulenga J, Derdeyn CA, Tang J, Heckerman D, Kaslow RA, Allen SA, Hunter E. (2012) Role of transmitted Gag CTL escape mutations in defining replicative capacity and early HIV-1 pathogenesis. PLoS Pathogens. 8(11):e1003041.

Garber DA, O'Mara LA, Gangadhara S, McQuoid M, Zhang X, Zheng R, Gill K, Verma M, Yu T, Johnson B, Li B, Derdeyn CA, Ibegbu C, Altman JD, Hunter E, Feinberg MB. (2012) Deletion of Specific Immune Modulatory Genes from Modified Vaccinia Ankara-Based HIV Vaccines Engenders Improved Immunogenicity in Rhesus Macaques. J Virol. 86(23):12605-15.

Basu D, Kraft CS, Murphy MK, Campbell PJ, Yu T, Hraber PT, Irene C, Pinmelater A, Chomba E, Mulenga J, Kilembe W, Allen SA, Derdeyn CA, Hunter E. (2012) HIV-1 subtype C superinfected individuals mount low autologous neutralizing antibody responses prior to intrasubtype superinfection. Retrovirology. 9(1):76.

Yu T. (2012) Receiver operating characteristic surface for class-skewed high-throughput data. PLoS ONE.7(7):e40598.

Adekambi T, Ibegbu CC, Kalokhe AS, Yu T, Ray SM, Rengarajan J. (2012) Distinct Effector Memory CD4(+) T Cell Signatures in Latent Mycobacterium tuberculosis Infection, BCG Vaccination and Clinically Resolved Tuberculosis. PLoS ONE. 7(4):e36046.

Wang C, Liu X, Huang H, Ma H, Cai W, Hou J, Dai Y, Yu T, Zhou, X. (2012) Deregulation of Snai2 is associated with metastasis and poor prognosis in tongue squamous cell carcinoma. Int. J of Cancer130(10):2249-58.

Ding X, Zhang N, Cai Y, Li S, Zheng C, Yi J, Yu T, Wang A, Zhou X. (2012) Down-regulation of tumor suppressor MTUS1/ATIP is associated with enhanced proliferation and poor prognosis of oral tongue squamous cell carcinoma. Molecular Oncology. 6(1):73-80.

Blackstock AJ, Manatunga AK#, Park Y, Jones DP, Yu T#. (2011) Clustering based on periodicity in high-throughput time course data. Stat. Anal. Data. Min. 4(6):579-589. (#Correspondence author)

Yu TBai Y. (2011) Capturing changes in gene expression dynamics by gene set differential coordination analysis. Genomics. 98(6):469-77.

 Park Y, Jones DP, Ziegler TR, Lee K, Kotha K, Yu T, Martin GS. (2011) Metabolic effects of albumin therapy in acute lung injury measured by proton nuclear magnetic resonance spectroscopy of plasma: A pilot study. Crit Care Med. 39(10):2308-13.

Yu TBai Y. (2011) Improving gene expression data interpretation by finding latent factors that co-regulate gene modules with clinical factors. BMC Genomics. 12:563. 

 Park Y, Le NH, Yu T, Strobel F, Miller NG, Accardi CJ, Lee KS, Wu S, Ziegler T, Jones DP. (2011) A sulfur amino acid-free meal increases plasma lipids in humans. J Nutr. 141(8):1424-31.

Holweg CTJ, Potena L, Luikart H, Yu T, Berry GJ, Cooke JP, Valantine HA, Mocarski ES. (2011) Identification and Classification of Acute Cardiac Rejection by Intragraft Transcriptional Profiling. Circulation. 24;123(20):2236-43.

Yu TPeng H, Sun W. (2011) Incorporating non-linear relationships in microarray missing value imputation. IEEE-ACM Trans. Comput. Biol. Bioinform. 8(3): 723-31.

Ghosh S, Tan F, Yu T, Li Y, Adisa O, Mosunjac M, Ofori-Acquah SF. (2011) Gene expression profiles of endothelial cells treated with hemin reveals a spatial and temporal complexity of the antioxidant enzyme defense in sickle cell disease. PLoS ONE. 6(3): e18399.

Jones DP, Park Y, Gletsu-Miller N, Liang Y, Yu T, Accardi CJ, Ziegler TR. (2011) Dietary sulfur amino acid effects on fasting plasma cysteine/cystine redox potential in humans. Nutrition. 27(2): 199-205.

Yu TPeng H. (2010) Quantification and deconvolution of asymmetric LC/MS peaks using the bi-Gaussian mixture model and statistical model selection. BMC Bioinformatics. 11:559 (10 pages). 

Johnson J, Yu T, Strobel F, Jones DP. (2010) Top-down metabolic profiling of human plasma using reproducible m/z features detected by LC-FTMS. Analyst. 135(11): 2864-70.

Yu T(2010) An exploratory data analysis method to reveal modular latent structures in high-throughput data. BMC Bioinformatics. 11:440 (13 pages).

Park Y, Ziegler TR, Gletsu-Miller N, Liang Y, Yu T, Accardi CJ, Jones DP. (2010) Postprandial cysteine/cystine redox potential in human plasma varies with meal content of sulfur amino acids. J Nutr. 140(4):760-5.

Mason CE, Shu FJ, Wang C, Session RM, Kallen RG, Sidell N, Yu T, Liu MH, Cheung E, Kallen CB. (2010) Location analysis for the estrogen receptor-alpha reveals binding to diverse ERE sequences and widespread binding within repetitive DNA elements. Nucleic Acids Res. 38(7): 2355-68.

Yu T, Park Y, Johnson JM, Jones DP. (2009) apLCMS – adaptive processing of high-resolution LC/MS data. Bioinformatics. 25(15): 1930-36. 

Sun W, Wright FA, Tang Z, Nordgard SH, Loo PV, Yu T, Kristensen VN, Perou CM. (2009) Integrated study of copy number states and genotype calls using high-density SNP arrays. Nucleic Acids Res. 37(16): 5365-77. 

Tan W, Sabet L, Li Y, Yu T, Klokkevold PR, Wong DT, Ho CM. (2009) Optical protein sensor for detecting cancer markers in saliva. Biosens Bioelectron. 24(2): 266-71.

Yu T, Ye H, Chen Z, Ziober BL, Zhou X (2008) Dimension reduction and mixed-effects model for microarray meta-analysis of cancer. Frontiers in Bioscience. 13:2714-20. 

Pillai VB, Hellerstein M, Yu T, Amara RR, Robinson HL. (2008) Comparative studies on in vitro expression and in vivo immunogenicity of supercoiled and open circular forms of plasmid DNA vaccines. Vaccine. 26(8): 1136-41.

Ye H, Wang A, Lee BS, Yu T, Sheng S, Peng T, Hu S, Crowe DL, Zhou X.(2008) Proteomic based identification of manganese superoxide dismutase 2 (SOD2) as a metastasis marker for oral squamous cell carcinoma. Cancer Genomics Proteomics. 5(2): 85-94.

Ye H*Yu T*, Temam S, Ziober B, Wang J, Schwartz JL, Mao L, Wong DT, Zhou X. (2008) Transcriptomic dissection of tongue squamous cell carcinoma. BMC Genomics. 9:69 (11 pages).  

Park NJ, Zhou X, Yu T, Brinkman BM, Zimmermann BG, Palanisamy V, Wong DT. (2007) Characterization of salivary RNA by cDNA library analysis. Arch Oral Biol. 52(1): 30-5.

Yu T, Ye H, Sun W, Li KC, Chen Z, Jacobs S, Bailey DK, Wong D, Zhou X. (2007) A forward-backward fragment assembling algorithm for the identification of genomic amplification and deletion breakpoints using high-density single nucleotide polymorphism (SNP) array. BMC Bioinformatics 8:145 (11 pages). 

Sun W, Yu T, Li KC. (2007) Detection of eQTL modules mediated by activity levels of transcription factors. Bioinformatics. 23(17): 2290-7.

Hu S, Yu T, Xie Y, Yang Y, Li Y, Zhou X, Tsung S, Loo RR, Loo JA, Wong DT. (2007) Discovery of Oral Fluid Biomarkers for Human Oral Cancer by Mass Spectrometry. Cancer Genomics Proteomics. 4: 55-64.

Lai L, Vodros D, Kozlowski PA, Montefiori DC, Wilson RL, Akerstrom VL, Chennareddi L, Yu T, Kannanganat S, Ofielu L, Villinger F, Wyatt LS, Moss B, Amara RR, Robinson HL. (2007) GM-CSF DNA: An adjuvant for higher avidity IgG, rectal IgA, and increased protection against the acute phase of a SHIV-89.6P challenge by a DNA/MVA immunodeficiency virus vaccine. Virology. 369(1):153-67.

Hu S, Wang J, Meijer J, Ieong S, Xie Y, Yu T, Zhou H, Henry S, Vissink A, Pijpe J, Kallenberg C, Elashoff D, Loo JA, Wong DT (2007) Salivary proteomic and genomic biomarkers for primary Sj?gren's syndrome. Arthritis Rheum. 56(11):3588-3600.

Robinson HL, Sharma S, Zhao J, Kannanganat S, Lai L, Chennareddi L, Yu T, Montefiori DC, Amara RR, Wyatt LS, Moss B. (2007) Immunogenicity in Macaques of the Clinical Product for a Clade B DNA/MVA HIV Vaccine: Elicitation of IFN-gamma, IL-2, and TNF-alpha Coproducing CD4 and CD8 T Cells. AIDS Res Hum Retroviruses.23(12):1555-62.

Park NJ, Yu T, Nabili V, Brinkman BM, Henry S, Wang J, Wong DT. (2006) RNAprotect Saliva: An Optimal Room-Temperature Stabilization Reagent for the Salivary TranscriptomeClin Chem. 52(12): 2303-4.

Xing Y*Yu T*, Wu Y, Roy M, Kim J, Lee C. (2006) An expectation-maximization algorithm for probabilistic reconstructions of full-length isoforms from splice graphs. Nucleic Acids Res, 34(10): 3150-60. 

Park NJ, Yang L, Yu T, Brinkman B, Wong DT. (2006) Characterization of RNA in Saliva. Clin Chem, 52(6): 988-94.

Yu T, Li KC. (2005) Inference of transcriptional regulatory network by two-stage constrained- space factor analysis. Bioinformatics, 21(21): 4033-8.

Yu T, Sun W, Yuan S, Li KC. (2005) Study of coordinative gene expression at the biological process level. Bioinformatics, 21(18): 3651-7.

Li KC, Liu CT, Sun W, Yuan S, Yu T. (2004) A system for enhancing genome-wide coexpression dynamics study. Proc Natl Acad Sci USA., 101(44): 15561-6. 

Pavlov D, Gerson JH, Yu T, Tobacman LS, Homsher E, Reisler E. (2003) The regulation of subtilisin-cleaved actin by tropomyosin/troponin. J Biol Chem., 278(8): 5517-22.

Park YD, Ou WB, Yu T, Zhou HM. (2001) Folding pathway for partially folded rabbit muscle creatine kinase. Biochem Cell Biol., 79(4):479-87.

Bai Y, Zhao Y, Yu T, Dierich MP, Chen YH. (2000) Antibodies to HIV-1 gp41 recognize synthetic peptides of human IFN-alpha and IFN-beta. Int Arch Allergy Immunol, 121(2):170-2.

Yu T, Xiao Y, Bai Y, Ru Q, Luo G, Dierich MP, Chen YH. (2000) Human interferon-beta inhibits binding of HIV-1 gp41 to lymphocyte and monocyte cells and binds the potential receptor protein P50 for HIV-1 gp41. Immunol Lett, 73(1):19-22.

Yu T, Bai Y, Dierich MP, Chen YH. (2000) Induction of High Levels of Epitope-Specific Antibodies by Epitope/Peptide Candidate Vaccines against HIV-1. Microbiol Immunol, 44(2):105-10.

Chen YH, Xiao Y, Yu T, Dierich MP. (1999) Epitope-Vaccine: a New Strategy Against HIV-1. Immunol Today, 20: 588-589.

Yang Y, Park YD, Yu T, Zhou HM. (1999) Reactivation and Refolding of a Partially Folded Creatine Kinase Modified by 5,5'-Dithio-bis (2-nitrobenzoic Acid). Biochem Biophys Res Commun, 259: 450-454.

Chen YH, Bai Y, Yu T, Dierich MP. (1999) Modulation of Major Histocompatibility Complex Antigen Expression by Human Immunodeficiency Virus-2 Gp36. Immunol Lett., 68: 415-417. 

Chen YH, Yu T, Bai Y, Dierich MP. (1999) Immunogenicity of the GPGRAFY epitope on Synthetic Peptides.Immunol Lett, 69:353-354.

Chen YH, Yu T, Bai Y, Zhao N. (1999) Two Proteins Share Immunological Epitopes on the Tumor-Associated Antigen 17-1A. Cancer Lett, 144: 101-105.

Chen YH, Speth C, Wu W, Stockl G, Xiao Y, Yu T, Ke Z, Zhao Y, Dierich MP. (1998) Antigenic characterization of HIV-1 gp41 binding proteins. Immunol Lett, 62(2):75-9.